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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 35.15
Human Site: S1060 Identified Species: 51.56
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 S1060 S E E S L L P S V G T K E A I
Chimpanzee Pan troglodytes XP_526380 1125 128795 S1111 S E E S L L P S V G T K E A I
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 S1060 S E E S L L P S V G T K E A I
Dog Lupus familis XP_545291 1075 123911 S1061 S E E S L L P S V G T K E A M
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 S1060 S E E N L L P S V G T K E A I
Rat Rattus norvegicus P70496 1074 123795 S1060 S E E N L L P S V G T K E A I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781 D282 V H G K A A R D V A R H F I Q
Chicken Gallus gallus XP_422793 1072 123414 S1058 E E E Y L L P S V G T K E S M
Frog Xenopus laevis NP_001129642 1039 119219 S1025 A E E N L L P S V G T K E A M
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 S1008 C E E N L M P S V G T K E H M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 P1350 N K E V L T P P G T S K E G L
Honey Bee Apis mellifera XP_001121004 1135 129725 A1121 C N E D L K P A A G T V E G I
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 G1413 C K A V L T P G I T S K E G L
Sea Urchin Strong. purpuratus XP_784455 790 90080 M777 D E N L Q P S M G E T E G L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 G1032 D Q E D L R P G F N E S E F Y
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 W1669 K E V E S R N W I F N S D R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 6.6 73.3 80 66.6 N.A. 33.3 46.6 26.6 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 86.6 100 86.6 N.A. 60 53.3 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 7 7 0 7 7 7 0 0 0 44 7 % A
% Cys: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 13 0 0 0 7 0 0 0 0 7 0 0 % D
% Glu: 7 69 75 7 0 0 0 0 0 7 7 7 82 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 7 0 0 7 7 0 % F
% Gly: 0 0 7 0 0 0 0 13 13 63 0 0 7 19 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 7 0 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 13 0 0 0 0 7 38 % I
% Lys: 7 13 0 7 0 7 0 0 0 0 0 69 0 0 0 % K
% Leu: 0 0 0 7 82 50 0 0 0 0 0 0 0 7 19 % L
% Met: 0 0 0 0 0 7 0 7 0 0 0 0 0 0 25 % M
% Asn: 7 7 7 25 0 0 7 0 0 7 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 7 82 7 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 13 7 0 0 0 7 0 0 7 0 % R
% Ser: 38 0 0 25 7 0 7 57 0 0 13 13 0 7 0 % S
% Thr: 0 0 0 0 0 13 0 0 0 13 69 0 0 0 0 % T
% Val: 7 0 7 13 0 0 0 0 63 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _